RESPIRATORY
CYSTIC FIBROSIS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Bone transplant from sibling
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Bone marrow transplant from sibling
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DNA transplant from sibling
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Cell takeout
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Detailed explanation-1: -Siblings have a 50% chance of being a half match, while parents are always a half match for their children, and vice versa. This gives a much better chance of finding a suitable donor.
Detailed explanation-2: -Most siblings donate their stem cells in a process called peripheral blood stem cell collection (PBSC). Some donate their bone marrow; this means they will need to have a small operation and a general anaesthetic to minimise discomfort during the procedure.
Detailed explanation-3: -Siblings are most often selected as a donor since they have the greatest chance (25%) of being HLA-matched with the recipient [1].
Detailed explanation-4: -People who have recently given birth can choose to donate their umbilical cord blood afterward. People in need can receive donated bone marrow from family members (related donors) or from people they don’t know (unrelated donors).