MRCP UK EXAMINATIONS

RESPIRATORY

FIBROTIC LUNG DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
CFTR is a strong conductance chloride channel, regulated by the cAMP pathway.
A
TRUE
B
False
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -The cystic fibrosis transmembrane conductance regulator (CFTR) protein helps to maintain the balance of salt and water on many surfaces in the body, such as the surface of the lung. When the protein is not working correctly, chloride-a component of salt-becomes trapped in cells.

Detailed explanation-2: -Abstract. Cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels are regulated tightly by protein kinases and phosphatases. The regulatory domain of CFTR has about 20 potential sites for phosphorylation by protein kinases A (PKA) and C (PKC).

There is 1 question to complete.