MRCP UK EXAMINATIONS

RESPIRATORY

OLD TUBERCULOSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A chronic case is considered suspected of multidrug-resistant tuberculosis (MDR-TB).
A
TRUE
B
false
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -Multidrug-resistant TB (MDR TB) is caused by TB bacteria that are resistant to at least isoniazid and rifampin, the two most potent TB drugs. These drugs are used to treat all persons with TB disease. TB experts should be consulted in the treatment of MDR TB.

Detailed explanation-2: -A confirmed MDR TB case is an MDR TB suspect who is sputum culture positive and whose TB is due to bacilli that are resistant in-vitro to at least isoniazid and rifampicin (the DST result being from an RNTCP accredited IRL).

Detailed explanation-3: -Multidrug-resistant TB (MDR TB) is caused by an organism that is resistant to at least isoniazid and rifampin, the two most potent TB drugs. These drugs are used to treat all persons with TB disease.

Detailed explanation-4: -Treatment of MDR-TB lasts for a long duration of approximately 2 years and consists of a combination of multiple second-line drugs, which are more expensive, less effective, and more toxic than the first-line drugs. Therefore, treatment outcomes for MDR-TB are poor, with a success rate of approximately 54% [2].

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