MRCP UK EXAMINATIONS

RESPIRATORY

OLD TUBERCULOSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The drugs administered in the intensive phase are:
A
Rifampin, isoniazid, and ethambutol
B
Rifampicin and isoniazid
C
Ethambutol pyrazinamide
D
Rifampicin, isoniazid, ethambutol and pyrazinamide
Explanation: 

Detailed explanation-1: -The first-line anti-tuberculosis (TB) regimen consists of rifampicin, isoniazid, pyrazinamide, and ethambutol, and correct management reduces risk of TB relapse and development of drug resistance.

Detailed explanation-2: -The preferred regimen for treating adults with TB remains a regimen consisting of an intensive phase of 2 months of isoniazid (INH), rifampin (RIF), pyrazinamide (PZA), and ethambutol (EMB) followed by a continuation phase of 4 months of INH and RIF.

Detailed explanation-3: -Four drugs-INH, RIF, PZA, and EMB-should be included in the initial treatment regimen until the results of drug-susceptibility tests are available.

Detailed explanation-4: -ETHAMBUTOL+ISONIAZID+PYRAZINAMIDE+RIFAMPICIN belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis. ETHAMBUTOL+ISONIAZID+PYRAZINAMIDE+RIFAMPICIN is a combination of four anti-tuberculosis drugs, namely: Rifampicin, isoniazid, pyrazinamide and ethambutol.

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