MRCP UK EXAMINATIONS

Detailed explanation-1: -Multibacillary leprosy: a 3-drug regimen of rifampicin 600 mg once a month (supervised), clofazimine 300 mg once a month (supervised) and 50 mg daily and dapsone 100 mg daily. At least 12 months of treatment must be taken within a period of 18 months.

Detailed explanation-2: -Hansen’s disease is treated with multidrug therapy (MDT) using a combination of antibiotics depending on the form of the disease: Paucibacillary form – 2 antibiotics are used at the same time, daily dapsone and rifampicin once per month. Multibacillary form – daily clofazimine is added to rifampicin and dapsone.

Detailed explanation-3: -The World Health Organization (WHO) recommends a multidrug therapy (MDT) consisting of rifampicin and dapsone for a fixed duration of 6 months in paucibacillary (PB) leprosy patients regardless of the clearance of skin lesions or presence or absence of acid–fast bacilli in the skin.