MRCP UK EXAMINATIONS

Detailed explanation-1: -Tuberculin test, also known as PPD test, is an intradermal test that diagnoses type IV hypersensitivity caused by tuberculosis bacillus infection by intradermal injection of tuberculin and according to the skin condition of the injection site.

Detailed explanation-2: -Type four hypersensitivity reaction is a cell-mediated reaction that can occur in response to contact with certain allergens resulting in what is called contact dermatitis or in response to some diagnostic procedures as in the tuberculin skin test.

Detailed explanation-3: -The TB skin test is performed by injecting a small amount of fluid (called tuberculin) into the skin on the lower part of the arm. A person given the tuberculin skin test must return within 48 to 72 hours to have a trained health care worker look for a reaction on the arm.

Detailed explanation-4: -The delayed-type hypersensitivity (DTH) to purified protein derivative (PPD) test has been used to infer about protective immunity to Mycobacterium tuberculosis and to diagnose tuberculosis.

Detailed explanation-5: -The Mantoux Test (MT) is a classical delayed-type hypersensitivity (DTH) response to the intradermal injection of tuberculin purified protein derivative (PPD). It represents a cutaneous T cell mediated memory recall immune response.