RESPIRATORY
OLD TUBERCULOSIS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Over 5 years of positive contact
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Silicosis
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Prior to administering anti-TNF biologic therapy with active TB
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Under 5 years of positive contact
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Detailed explanation-1: -The World Health Organization recommends that all children below the age of five who have household contact with an infectious tuberculosis case should receive isoniazid preventive treatment for at least six months after the active tuberculosis disease has been ruled out.
Detailed explanation-2: -TPT is only given to people who are infected with TB bacteria or have been exposed to it and are at a higher risk of developing TB disease than the general population. TPT is considered one of the most critical public health measures to protect both individuals and the community from TB.
Detailed explanation-3: -Alternative treatments for latent TB infection in children include 4 months of daily rifampin or 9 months of daily isoniazid.
Detailed explanation-4: -The usual preventive therapy regimen is isoniazid (10 mg/kg daily for children, up to a maximum adult dose of 300 mg daily). The recommended duration of isoniazid preventive treatment varies from 6 to 12 months of continuous therapy (9).
Detailed explanation-5: -The World Health Organization recommends isoniazid preventive therapy (IPT) for preventing tuberculosis in HIV-infected adults, although few countries have instituted this policy. Both IPT and highly active antiretroviral therapy (HAART) used separately result in reductions in tuberculosis risk.