RESPIRATORY
OLD TUBERCULOSIS
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Mode of transmission is by inhalation.
|
|
|
The vast majority of M. tuberculosis infected individuals will not develop active tuberculosis.
|
|
|
Reactivation of tuberculosis can be triggered by immunosuppression.
|
|
|
Co-infection with HIV reduces the risk of developing active tuberculosis
|
|
|
M. tuberculosis encounter the dendritic cells in the trachea.
|
Detailed explanation-1: -After antibiotic treatment, reactivation of the infection can occur spontaneously or in response to immunosuppressive agents, such as glucocorticoids.
Detailed explanation-2: -Transmission of TB is by inhalation of infectious droplet nuclei containing viable bacilli (aerosol spread). Mycobacteria-laden droplet nuclei are formed when a patient with active pulmonary TB coughs and can remain suspended in the air for several hours. Sneezing or singing may also expel bacilli.
Detailed explanation-3: -Immunosuppression during Active Tuberculosis Is Characterized by Decreased Interferon- Production and CD25 Expression with Elevated Forkhead Box P3, Transforming Growth Factor-, and Interleukin-4 mRNA Levels.
Detailed explanation-4: -Reactivation tuberculosis, as the name suggests, is the reactivation of contained mycobacterial infection. Reactivation Tb is the most common form of active tuberculosis, representing 90% of the cases.