MRCP UK EXAMINATIONS

RESPIRATORY

OLD TUBERCULOSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What did Robert Koch reveal the ingredients of Tuberculin to be?
A
Anthrax bacteria in glycerin extract
B
Active tuberculosis microbes in glycerin extract
C
Tuberculosis bacteria only
D
Dead tuberculosis microbes in glycerin extract
E
Dead cholera microbes in glycerin extract
Explanation: 

Detailed explanation-1: -Although it was suspected that tuberculosis was caused by an infectious agent, the organism had not yet been isolated and identified. By modifying the method of staining, Koch discovered the tubercle bacillus and established its presence in the tissues of animals and humans suffering from the disease.

Detailed explanation-2: -Aplisol (tuberculin PPD, diluted) is a sterile aqueous solution of a purified protein fraction for intradermal administration as an aid in the diagnosis of tuberculosis. The solution is stabilized with polysorbate (Tween) 80, buffered with potassium and sodium phosphates and contains 0.25% phenol as a preservative.

Detailed explanation-3: -Koch continued his studies on tuberculosis, hoping to find a cure. In 1890, he announced the discovery of tuberculin, a substance derived from tubercle bacilli, which he thought was capable of arresting bacterial development in vitro and in animals.

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