RESPIRATORY
OLD TUBERCULOSIS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Timely detection and cure of all new cases (with supervised schemes)
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Encourage the use of face masks
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Isoniazid preventive therapy
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None of the above
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Detailed explanation-1: -The most important way to prevent the spread of drug-resistant TB is to take all TB drugs exactly as prescribed by the health care provider. No doses should be missed and treatment should not be stopped early.
Detailed explanation-2: -Isoniazid-Resistant Tuberculosis (Rifampin Susceptible) Treatment with rifampin, ethambutol, pyrazinamide, and levofloxacin recommended for a duration of 6 months.
Detailed explanation-3: -The main mechanism of development of fluoroquinolone resistance in M. tuberculosis is by chromosomal mutations in the quinolone resistance-determining region of gyrA or gyrB. The most frequent mutations found are at position 90 and 94 of gyrA but mutations at position 74, 88 and 91 have also been reported [78, 79].
Detailed explanation-4: -DOT helps prevent TB from spreading to others. DOT decreases the risk of drug-resistance resulting from erratic or incomplete treatment.