MRCP UK EXAMINATIONS

RESPIRATORY

OLD TUBERCULOSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the cut-off point to consider PPD positive in latent TB?
A
< 5 mm
B
> 15 mm
C
> 5 mm
D
3-4 mm
Explanation: 

Detailed explanation-1: -According to CDC, the repeat PPD Skin test is considered positive if there is ≥ 10 mm induration and the induration is increased by ≥6 mm compared to the previous test. This test interpretation is less sensitive but more specific.

Detailed explanation-2: -A patient who does not return within 72 hours will probably need to be rescheduled for another skin test. * For employees who are otherwise at low risk for TB and who are tested as part of an infection control screening program at the start of employment, a reaction of 15 mm is considered positive.

Detailed explanation-3: -The PPD skin test is a method used to diagnose silent (latent) tuberculosis (TB) infection. PPD stands for purified protein derivative. The positive immunologic response to PPD antigen is seen here. The size of the papule is over 2 cm in diameter.

Detailed explanation-4: -A “positive” TB blood test result means you probably have TB germs in your body. Most people with a positive TB blood test have latent TB infection. To be sure, your doctor will examine you and do a chest x-ray. You may need other tests to see if you have latent TB infection or active TB disease.

Detailed explanation-5: -The Tuberculin Skin Test (TST) Tuberculin positivity manifests as induration at the site of testing after 48 hours. Induration less than 5 mm diameter following a standard injection of 5 units PPD is regarded as negative and greater than 10 mm diameter as positive.

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