RESPIRATORY
OLD TUBERCULOSIS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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A) Erhaz / 4 (Ir) (4 AH)
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B) 4RHZE/2(3H)(3H)
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Q) Erhaz / 4 (Ar) (PBUH)
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d) Erhaz / 4 (Ar) (pbuh)
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Detailed explanation-1: -The 4-month rifapentine-moxifloxacin regimen has an intensive phase of 8 weeks of daily treatment with rifapentine, isoniazid, pyrazinamide, and moxifloxacin followed by a continuation phase of 9 weeks of daily treatment with rifapentine, isoniazid, and moxifloxacin (a total of 17 weeks for treatment).
Detailed explanation-2: -Treatment is given in two phases: Continuation phase consists of 16 weeks (112 doses) of isoniazid, rifampicin and ethambutol in daily dosages. Only pyrazinamide will be stopped in the continuation phase. The CP needs to be extended upto 24 weeks in certain forms of TB like CNS TB, Skeletal TB.
Detailed explanation-3: -For initial empiric treatment of TB, start patients on a 4-drug regimen: isoniazid, rifampin, pyrazinamide, and either ethambutol or streptomycin. Once the TB isolate is known to be fully susceptible, ethambutol (or streptomycin, if it is used as a fourth drug) can be discontinued.
Detailed explanation-4: -First-line agents for treatment of TB disease consist of isoniazid, a rifamycin (rifampin or [less frequently] either rifapentine or rifabutin), pyrazinamide, and ethambutol; in addition, moxifloxacin is a first-line agent when administered in combination with isoniazid, rifapentine, and pyrazinamide [6].