MRCP UK EXAMINATIONS

Detailed explanation-1: -The usual treatment is: 2 antibiotics (isoniazid and rifampicin) for 6 months. 2 additional antibiotics (pyrazinamide and ethambutol) for the first 2 months of the 6-month treatment period.

Detailed explanation-2: -Isoniazid: 9-month Regimen. A 9-month INH regimen is considered optimal treatment. In order to be considered adequate treatment, the patient must receive a minimum of 270 doses administered within 12 months. Patients may be treated with a twice-weekly regimen as an alternative as long as they are undergoing DOT.

Detailed explanation-3: -After taking TB medicine for several weeks, a doctor will be able to tell TB patients when they are no longer able to spread TB germs to others. Most people with TB disease will need to take TB medicine for at least 6 months to be cured.

Detailed explanation-4: -To ensure that these goals are met, TB disease must be treated for at least 6 months and in some cases even longer. Most of the bacteria are killed during the first 8 weeks of treatment; however, there are persistent organisms that require longer treatment.

Detailed explanation-5: -In 1991, an eight months treatment regimen composed of 2 months intensive with Isoniazid(H), Rifampicin (R), Pyrazinamide(Z) and Ethambutol(E) (2RHZE/S) and 6 months continuation (6HE) phases were recommended for all new cases of TB across the world [6].