MRCP UK EXAMINATIONS

RESPIRATORY

OLD TUBERCULOSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the antituberculous drugs is considered second line?
A
isoniacida
B
ethambutol
C
piraji tears
D
etionacid
E
rifampicin
Explanation: 

Detailed explanation-1: -Ethambutol, Pyrazinamide, Thioamides, Cycloserine, Para-aminosalicylic acid, Streptomycin, and Clofazimine are possibly effective. Kanamycin, Capreomycin and Amikacin are injectable second-line.

Detailed explanation-2: -First-line agents for treatment of TB disease consist of isoniazid, a rifamycin (rifampin or [less frequently] either rifapentine or rifabutin), pyrazinamide, and ethambutol; in addition, moxifloxacin is a first-line agent when administered in combination with isoniazid, rifapentine, and pyrazinamide [6].

Detailed explanation-3: -The first-line therapeutic drugs are the most effective and least toxic for use in the treatment of TB, while the second-line therapeutic drugs are less effective, more expensive and have higher toxicities. They are however, essential for the treatment of drug resistant forms of the bacteria (MDR-TB).

There is 1 question to complete.