GENERAL HISTOLOGY

Detailed explanation-1: -Even though bones stop growing in length in early adulthood, they can continue to increase in thickness or diameter throughout life in response to stress from increased muscle activity or to weight. The increase in diameter is called appositional growth.

Detailed explanation-2: -Endochondral bone formation occurs when hyaline cartilage is used as a precursor to bone formation, then bone replaces hyaline cartilage, forms and grows all other bones, occurs during development and throughout life.

Detailed explanation-3: -Appositional growth can occur at the endosteum or peristeum where osteoclasts resorb old bone that lines the medullary cavity, while osteoblasts produce new bone tissue.

Detailed explanation-4: -This growth can be commonly observed after birth of an individual but generally in the first trimester that is around fourth or fifth week the development of bones and stops growing at the age of 21 for males and comparatively in female at lesser age of 18.