GENERAL HISTOLOGY

Detailed explanation-1: -The nephron loop is the U-shaped bend of a nephron which extends through the medulla of the kidney. Histologically, it consists of two parts; thin descending and thin ascending limbs. Both limbs are composed of simple squamous epithelium.

Detailed explanation-2: -Henle’s loop is a U-shaped long portion of the tubule structure of a nephron that helps in the conduction of urine. The main function of this structure is to reabsorb water and sodium chloride (NaCl) from urine.

Detailed explanation-3: -Question: Why are the two parts of the nephron loop called descending and ascending? (a) The descending loop is the portion that carries filtrate deep into the renal medulla, away from the cortex. The ascending loop carries filtrate back toward the kidney surface.

Detailed explanation-4: -The key difference between ascending and descending loop of Henle is that ascending loop of Henle is the thicker segment of the loop of Henle located just after the sharp bend of the loop while descending loop of Henle is the thinner segment located just before the sharp bend of the loop.