GENERAL HISTOLOGY

Detailed explanation-1: -Osteoblasts, osteocytes and osteoclasts are the three cell types involved in the development, growth and remodeling of bones. Osteoblasts are bone-forming cells, osteocytes are mature bone cells and osteoclasts break down and reabsorb bone. There are two types of ossification: intramembranous and endochondral.

Detailed explanation-2: -Under the direction of osteocytes, osteoblasts continuously build up bone, while osteoclasts continuously break down bone to maintain mineral homeostasis. Bone tissues include compact bone, spongy bone, bone marrow, and periosteum.

Detailed explanation-3: -Osteocytes regulate local mineral deposition and chemistry at the bone matrix level, and they also function as endocrine cells producing factors that target distant organs such as the kidney to regulate phosphate transport. Osteocytes appear to be the major local orchestrator of many of bone’s functions.