GENERAL HISTOLOGY

BONE

DEVELOPING BONE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
During endochondral ossification, what is the third step?
A
cartilage starts to calcify and periosteal bone collar forms
B
the epiphyseal plates are ossified
C
primary ossification centers form in the diaphysis
D
hyaline cartilage develops and is a model
Explanation: 

Detailed explanation-1: -Primary ossification center forms in the diaphyseal region of the periosteum called the periosteal collar. Secondary ossification centers develop in the epiphyseal region after birth.

Detailed explanation-2: -The osteoblasts form a collar of compact bone around the diaphysis. At the same time, the cartilage in the center of the diaphysis begins to disintegrate. Osteoblasts penetrate the disintegrating cartilage and replace it with spongy bone. This forms a primary ossification center.

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