GENERAL HISTOLOGY

Detailed explanation-1: -These proliferative areas become the epiphyseal plates (physeal plates/growth plates), which provide longitudinal growth of bones after birth and into early adulthood. After birth, this entire process repeats itself in the epiphyseal region; this is where the secondary ossification center forms [3].

Detailed explanation-2: -Later, usually after birth, secondary ossification centers form in the epiphyses. Ossification in the epiphyses is similar to that in the diaphysis except that the spongy bone is retained instead of being broken down to form a medullary cavity.

Detailed explanation-3: -In endochondral ossification, bone develops by replacing hyaline cartilage. Activity in the epiphyseal plate enables bones to grow in length (this is interstitial growth). Appositional growth allows bones to grow in diameter.