GENERAL HISTOLOGY

BONE

OSSIFICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Blood vessels penetrate the diaphysis
A
Step 1:Collar bone formation
B
Step 2:Cavitation
C
Step 3. Diaphysis Elongation
D
Step 4:Epiphyseal Ossification
Explanation: 

Detailed explanation-1: -Endochondral ossification can be divided into five stages: commitment, compaction, proliferation, growth, and finally, chondrocyte death and the generation of new bone. Phases 1 and 2: commitment and compaction. First, the mesenchymal cells commit to becoming cartilage (Figure 1A).

Detailed explanation-2: -Figure 6.16 Intramembranous Ossification Intramembranous ossification follows four steps. (a) Mesenchymal cells group into clusters, and ossification centers form. (b) Secreted osteoid traps osteoblasts, which then become osteocytes. (c) Trabecular matrix and periosteum form.

Detailed explanation-3: -Reserve Zone. Storage site for lipids, glycogen, proteoglycan. Proliferative Zone. Proliferating chondrocytes leading to longitudinal growth. Hypertrophic Zone. Site of chondrocyte maturation. Primary Spongiosa. Site for mineralization to form woven bone. Secondary Spongiosa. 08-May-2022

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