GENERAL HISTOLOGY

BONE

OSSIFICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Cells that break down the calcified matrix of bone:
A
osteoblasts
B
osteoclasts
C
osteons
D
osteocytes
Explanation: 

Detailed explanation-1: -Osteoblasts are bone-forming cell, osteoclasts resorb or break down bone, and osteocytes are mature bone cells. An equilibrium between osteoblasts and osteoclasts maintains bone tissue .

Detailed explanation-2: -Osteoclasts dissolve bone mineral by massive acid secretion and secrete specialized proteinases that degrade the organic matrix, mainly type I collagen, in this acidic milieu.

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