GENERAL HISTOLOGY

BONE

OSSIFICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In time, the hyaline cartilage starts to break down and disintegrate. What happens next?
A
Muscles will be attached to bone with tendons
B
Osteoblasts will replace it with cancellous bone
C
Calcium will be needed for blood clotting
D
Vitamin B will regulate fluid levels
Explanation: 

Detailed explanation-1: -Osteoblasts penetrate the disintegrating cartilage and replace it with spongy bone. This forms a primary ossification center. Ossification continues from this center toward the ends of the bones.

Detailed explanation-2: -The bone matrix then surrounds the osteoblast cells, which are converted to mature bone cells known as osteocytes. Osteocytes produce the components essential for maintaining the bone matrix. Osteoclasts are the bone cells with several nuclei that are derived from the stem cells present in red bone marrow.

Detailed explanation-3: -After the process of bone formation, matrix synthesising osteoblasts have three potential fates: Some osteoblasts become flattened and remain as quiescent lining cells at the bone surface and some die by apoptosis.

Detailed explanation-4: -Osteoclasts constantly break down and reabsorb old bone tissue, while osteoblasts form new bone tissue. Together, these two cells control the gradual reshaping of the bones.

There is 1 question to complete.