GENERAL HISTOLOGY

BONE

OSSIFICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The epiphyseal cartilage starts to form; separation of the epiphysis from the diaphysis
A
Stage 1:Bone Collar Formation
B
Stage 2:Cavitation
C
Stage 3:Diaphysis Elongation
D
Stage 4:Epiphyseal Ossification
Explanation: 

Detailed explanation-1: -The anterior epiphysis commences ossification first at around 12-13 years of age in females and 14-15 years of age in males.

Detailed explanation-2: -In children and young adults, the epiphyses are separated from the diaphysis by epiphyseal cartilage or plates, where bone grows in length. Estrogen and testosterone release at puberty initiates closure of the epiphyseal plates.

Detailed explanation-3: -During stage 3 of long bone growth, two secondary centers of ossification form in epiphyseal area.

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