GENERAL HISTOLOGY

BONE

OSSIFICATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What/who will break down the newly formed bone to create a medullary cavity?
A
Potassium, which maintains a chemical and fluid balance
B
The sesamoid bone
C
Osteoclasts (cells that destroy bone)
D
The epiphyseal plates
Explanation: 

Detailed explanation-1: -During appositional growth, osteoclasts resorb old bone that lines the medullary cavity, while osteoblasts, via intramembranous ossification, produce new bone tissue beneath the periosteum. Mesenchymal stem cell migration and differentiation are two important physiological processes in bone formation.

Detailed explanation-2: -OSTEOBLASTS are the cells that form new bone. They also come from the bone marrow and are related to structural cells. They have only one nucleus. Osteoblasts work in teams to build bone.

Detailed explanation-3: -Blood vessels invade the cavities, and osteoblasts and osteoclasts modify the calcified cartilage matrix into spongy bone. Osteoclasts then break down some of the spongy bone to create a marrow, or medullary, cavity in the center of the diaphysis.

Detailed explanation-4: -Osteoclasts are the cells that degrade bone to initiate normal bone remodeling and mediate bone loss in pathologic conditions by increasing their resorptive activity. They are derived from precursors in the myeloid/monocyte lineage that circulate in the blood after their formation in the bone marrow.

There is 1 question to complete.