GENERAL HISTOLOGY

Detailed explanation-1: -The epiphyseal bone plate is formed by ossification of the lower part of the epiphyseal cartilage after the development of the secondary ossification center. At the beginning, the secondary ossification center expands in all directions to form spongy bone trabeculae with a radial orientation.

Detailed explanation-2: -In the fetus, the primary ossification centre forms first in the diaphysis. Later on a secondary ossification centre forms in the epiphyses. Cartilage is replaced by bone in the epiphysis and diaphysis, except in the epiphyseal plate region. Here the bone continues to grow, until maturity (around 18 years old).