GENERAL HISTOLOGY

Detailed explanation-1: -Osteoblasts are cells that form bone tissue . Osteoblasts can synthesize and secrete bone matrix and participate in the mineralization of bone to regulate the balance of calcium and phosphate ions in developing bone. Osteoblasts are derived from osteoprogenitor cells .

Detailed explanation-2: -Osteoblasts are cells responsible for the secretion and deposition of bone morphogenetic proteins (BMPs) into the extracellular matrix during bone formation.

Detailed explanation-3: -Bone matrix is synthesized by a layer of osteoblasts on the bone surface (Figs. 1-22 and 1-23). The osteoblasts are mesenchymal in origin and characterized by their abundant endoplasmic reticulum and their production of the enzyme alkaline phosphatase.

Detailed explanation-4: -The bone matrix eventually grows to surround osteoblasts and the bone material becomes calcified. Once surrounded and trapped, the osteoblast becomes a mature bone cell referred to as an osteocyte.