GENERAL HISTOLOGY

Detailed explanation-1: -The cartilage is a connective tissue that contains cells embedded in a matrix of chondrin. Chondrin is made up of two proteins chondroalbunoid and chondromucoid.

Detailed explanation-2: -Collagen type II-Collagen type II is the major structural protein in cartilage ECM (∼85%) and the major collagen found in the growth plate during endochondral ossification [61]. It is primarily found in the matrix secreted by the reserve zone chondrocytes.

Detailed explanation-3: -The most abundant matrix protein in bone is type I collagen. Collagen contributes to the mechanical properties of bone and is necessary for calcification of the tissue. In addition to collagen, several acidic proteins are present as minor components.

Detailed explanation-4: -Chondrin is a gelatin-like protein-carbohydrate substance that forms a matrix in cartilage to embed cartilage cells. Whereas, bones contain collagen proteins known as Ossein. The combination of collagen and calcium makes the bone strong and flexible to withstand stress.