GENERAL HISTOLOGY

CONNECTIVE TISSUE GLAND

CONNECTIVE TISSUE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Fixed macrophages usually have a specific name depend on where it is located in the body, so where are the Kupffer cell locate in the body?
A
Bone
B
Epidermis
C
Lungs
D
Liver
E
Lymph nodes
Explanation: 

Detailed explanation-1: -The Kupffer cell is located to the hepatic sinusoid and is therefore in close proximity to other cells in the sinusoid, including natural killer (NK) and natural killer T cells (NKT), as well as the liver sinusoidal endothelial cells (LSEC).

Detailed explanation-2: -Kupffer cells are macrophages that are fixed within the sinusoids of the liver. They are the body’s most abundant source of fixed macrophages.

Detailed explanation-3: -Monocyte-derived macrophages can mainly be found at the portal triad in the healthy liver, where they contribute to iron and cholesterol metabolism7, 23.

Detailed explanation-4: -In the liver, macrophages are called Kupffer cells. They line tiny blood vessels in the liver, where they do a lot of things, including maintaining the body’s iron levels and clearing away endotoxins produced by gut bacteria.

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