CONNECTIVE TISSUE GLAND
CONNECTIVE TISSUE
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
presence of a prominent, clear area in the cytoplasm that is adjacent to the nucleus
|
|
|
a large number of metachromatic granules with different density
|
|
|
a large number of lysosomes and phagosomes
|
|
|
well developed granular endoplasmic reticulum, Golgi complex and mitochondria
|
|
|
a large number of small fat drops and mitochondria
|
Detailed explanation-1: -Macrophages internalize pathogens through phagocytosis, entrapping them into organelles called phagosomes. Phagosomes then fuse with lysosomes to mature into phagolysosomes, acquiring an acidic and hydrolytic lumen that kills the pathogens.
Detailed explanation-2: -Histiocyte and dendritic cell lineages Human DCs are classified into 2 main groups: plasmacytoid and myeloid (mDC). mDCs have been further subdivided into 2 subsets on the basis of their expression of CD141 (mDC1) and CD1c (mDC2).
Detailed explanation-3: -A histiocyte is a normal immune cell that is found in many parts of the body especially in the bone marrow, the blood stream, the skin, the liver, the lungs, the lymph glands and the spleen. In histiocytosis, the histiocytes move into tissues where they are not normally found and cause damage to those tissues.
Detailed explanation-4: -Phagocytes engulf unwanted particles into phagosomes that then fuse with lysosomes to degrade the enclosed particles.