GENERAL HISTOLOGY

Detailed explanation-1: -Answer and Explanation: In adults, connective tissue originates and arises from the mesoderm. The mesoderm is characterized as being the middle germ layer.

Detailed explanation-2: -During embryogenesis, mesenchyme gives rise to the body’s connective tissues, from cartilage and bone to fat, muscle, and the circulatory system.

Detailed explanation-3: -All connective tissues have a common origin from mesenchyme and are composed of separated cells and abundant intercellular substance, or matrix. The latter is composed of fibers, amorphous ground substance, and tissue fluid.

Detailed explanation-4: -Mesenchyme is an embryonic precursor tissue that generates a range of structures in vertebrates including cartilage, bone, muscle, kidney and the erythropoietic system. Mesenchyme originates from both mesoderm and the neural crest, an ectodermal cell population, via an epithelial to mesenchymal transition (EMT).

Detailed explanation-5: -Mesenchymal stem cells (MSCs) are multipotent stem cells that can differentiate into a variety of cell types, including bone cells (osteoblasts), cartilage cells (chondrocytes), muscle cells (myocytes) and fat cells that give rise to marrow adipose tissue (adipocytes).