GENERAL HISTOLOGY

Detailed explanation-1: -Bone is a mineralized connective tissue that exhibits four types of cells: osteoblasts, bone lining cells, osteocytes, and osteoclasts [1, 2].

Detailed explanation-2: -Osteocytes, the cells residing within the bone matrix, make up between 90% to 95% of the cellular component in skeletally mature adult bone tissue.

Detailed explanation-3: -osteocyte, a cell that lies within the substance of fully formed bone. It occupies a small chamber called a lacuna, which is contained in the calcified matrix of bone. Osteocytes derive from osteoblasts, or bone-forming cells, and are essentially osteoblasts surrounded by the products they secreted.

Detailed explanation-4: -Osteocytes are the longest living bone cell, making up 90–95% of cells in bone tissue in contrast to osteoclasts and osteoblasts making up  5% (40). Osteocytes form when osteoblasts become buried in the mineral matrix of bone and develop distinct features.

Detailed explanation-5: -Osteoblasts/osteocytes develop in mesenchyme. In mature bones, osteocytes and their processes reside inside spaces called lacunae (Latin for a pit) and canaliculi, respectively. Osteocytes are simply osteoblasts trapped in the matrix that they secrete.