GENERAL HISTOLOGY

Detailed explanation-1: -The fibrous proteins produced by fibroblasts mainly consist of fibrin, fibronectin, and collagen. Fibrin and fibronectin provide a basic framework for cells to stick together and form a tissue, whilst collagen provides the mechanical strength needed for the tissue strength.

Detailed explanation-2: -Fibroblasts produce the ECM’s structural proteins (e.g., fibrous collagen and elastin), adhesive proteins (e.g., laminin and fibronectin), and ground substance (e.g., glycosaminoglycans, such as hyaluronan and glycoproteins). However, fibroblasts also play various additional roles beyond ECM production.

Detailed explanation-3: -Fibroblasts produce and secrete all components of the ECM, including the structural proteins, adhesive proteins, and a space-filling ground substance composed of glycosaminoglycans and proteoglycans.

Detailed explanation-4: -A type of tissue that is mostly made up of tough protein fibers called collagen and cells called fibroblasts. Fibrous connective tissue supports, protects, and holds bones, muscles, and other tissues and organs in place.

Detailed explanation-5: -They secrete the fibers (notably collagen and elastin) and ground substance of the extracellular matrix. Fibroblasts are often spindle-shaped with an elongated nucleus.