GENERAL HISTOLOGY

CONNECTIVE TISSUE GLAND

CONNECTIVE TISSUE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The main function of fibroblasts:
A
synthesis of the intercellular substance
B
storage of the reserve fat
C
melanin synthesis
D
immunoglobulin synthesis
E
hormone synthesis
Explanation: 

Detailed explanation-1: -Fibroblasts’ most well-known biological role is the production of the rich ECM of connective tissues. Fibroblasts produce and secrete all components of the ECM, including the structural proteins, adhesive proteins, and a space-filling ground substance composed of glycosaminoglycans and proteoglycans.

Detailed explanation-2: -Human fibroblasts synthesize elevated levels of extracellular matrix proteins in response to interleukin 4.

Detailed explanation-3: -The primary function of fibroblasts is the maintenance of structural integrity within the connective tissue. They achieve this by secreting extracellular matrix precursors required for formation of the connective tissue and various fibres.

Detailed explanation-4: -The fibrous proteins produced by fibroblasts mainly consist of fibrin, fibronectin, and collagen. Fibrin and fibronectin provide a basic framework for cells to stick together and form a tissue, whilst collagen provides the mechanical strength needed for the tissue strength.

There is 1 question to complete.