GENERAL HISTOLOGY

Detailed explanation-1: -The matrix is hardened by the binding of inorganic mineral salt, calcium phosphate, in a chemical arrangement known as bone mineral, a form of calcium hydroxylapatite. It is the mineralization that gives bones rigidity.

Detailed explanation-2: -The ground substance is the nonfibrillar organic component of the bone matrix and it fills the space around the collagen fibrils and hydroxyapatite crystals. The ground substance contains glycoproteins, proteoglycans, and glycosaminoglycans.

Detailed explanation-3: -Bone is comparable to all connective tissues in that it consists of cells and an intercellular substance. In bone, the intercellular matrix consists of collagen fibers and mineral salts, mostly calcium phosphate (85%), but also calcium carbonate (10%), in addition to magnesium and alkali salts (5%).

Detailed explanation-4: -Collagen is the most abundant component of the extracellular bone matrix. In addition to collagen, bone matrix contains approximately 180 to 200 NCPs.

Detailed explanation-5: -Bone matrix is the intercellular substance of bone tissue. Organic and inorganic components make up the bone matrix. The organic component of the bone matrix mainly comprises collagen. The inorganic component (calcium phosphate, mostly hydroxyapatite crystals) makes up 67% of the bone matrix.