GENERAL HISTOLOGY

Detailed explanation-1: -Connective tissues are made up of a matrix consisting of living cells and a non-living substance, called the ground substance. The ground substance is made of an organic substance (usually a protein) and an inorganic substance (usually a mineral or water). The principal cell of connective tissues is the fibroblast.

Detailed explanation-2: -A. All connective tissue has an extracellular matrix, cells and fibers are held in place by this ground substance that varies from semi-fluid to solid. The matrix is related to the function of each tissue type.

Detailed explanation-3: -Elastic fibers are long, thin fibers that form branching network in the extracellular matrix. They help the connective tissue to stretch and recoil.

Detailed explanation-4: -Fibroblast Fibroblasts are by far the most common native cell type of connective tissue. The fibroblast synthesizes the collagen and ground substance of the extracellular matrix. These cells make a large amount of protein that they secrete to build the connective tissue layer.

Detailed explanation-5: -The ‘ground substance’ of extracellular matrix is an amorphous gelatinous material. It is transparent, colourless, and fills the spaces between fibres and cells. It actually consists of large molecules called glycosoaminoglycans (GAGs) which link together to form even larger molecules called proteoglycans.