GENERAL HISTOLOGY

Detailed explanation-1: -The ‘ground substance’ of extracellular matrix is an amorphous gelatinous material. It is transparent, colourless, and fills the spaces between fibres and cells. It actually consists of large molecules called glycosoaminoglycans (GAGs) which link together to form even larger molecules called proteoglycans.

Detailed explanation-2: -Unlike epithelial tissue, which is composed of cells closely packed with little or no extracellular space in between, connective tissue cells are dispersed in a matrix. The matrix usually includes a large amount of extracellular material produced by the connective tissue cells that are embedded within it.

Detailed explanation-3: -Blood is a connective tissue that has a fluid matrix, called plasma, and no fibers. Erythrocytes (red blood cells), the predominant cell type, are involved in the transport of oxygen and carbon dioxide. Also present are various leukocytes (white blood cells) involved in immune response.

Detailed explanation-4: -Ground substance is a gel-like material that fills the spaces between connective tissue cells. It is a mixture of glycoproteins, glycoaminoglycans (such as hyaluronic acid), and proteoglycans. Ground substance can be very fluid, as in the vitreous humor in the posterior cavity of the eye, or calcified, as in a bone.

Detailed explanation-5: -In biology, the extracellular matrix (ECM), also called intercellular matrix, is a three-dimensional network consisting of extracellular macromolecules and minerals, such as collagen, enzymes, glycoproteins and hydroxyapatite that provide structural and biochemical support to surrounding cells.