GENERAL HISTOLOGY

CONNECTIVE TISSUE GLAND

CONNECTIVE TISSUE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which type of cells produce the matrix in bone?
A
Adiposites
B
Chondrocytes
C
Osteocytes
D
Fibroblasts
Explanation: 

Detailed explanation-1: -Osteoblasts are cells responsible for the secretion and deposition of bone morphogenetic proteins (BMPs) into the extracellular matrix during bone formation.

Detailed explanation-2: -Osteocytes are derived from mesenchymal stem cells through osteoblast differentiation. Their entrapment within the bone matrix is possibly an active process and an embedment in neighbor osteoid forming osteoblasts (Bonewald, 2011).

Detailed explanation-3: -The pericellular matrix (PCM) surrounds the osteocyte and separates the cell from the walls of the lacunae and canaliculi. This matrix contains proteoglycans and hyaluronic acid and may amplify the impacts of mechanical loading to allow osteocyte to sense more load than what would be calculated by tissue strain alone.

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