GENERAL HISTOLOGY

Detailed explanation-1: -Addison’s disease, also called adrenal insufficiency, is an uncommon illness that occurs when the body doesn’t make enough of certain hormones. In Addison’s disease, the adrenal glands make too little cortisol and, often, too little of another hormone, aldosterone.

Detailed explanation-2: -This is called an autoimmune disorder. Addison’s disease can develop if your immune system attacks your adrenal glands and severely damages your adrenal cortex. When 90% of the adrenal cortex is destroyed, your adrenal glands will not be able to produce enough of the steroid hormones cortisol and aldosterone.

Detailed explanation-3: -Addison’s disease is usually the result of a problem with the immune system, which causes it to attack the outer layer of the adrenal gland (the adrenal cortex), disrupting the production of the steroid hormones aldosterone and cortisol.

Detailed explanation-4: -The hypothalamus produces corticotropin-releasing hormone (CRH) that stimulates the pituitary gland to secrete adrenocorticotropin hormone (ACTH). ACTH then stimulates the adrenal glands to make and release cortisol hormones into the blood.

Detailed explanation-5: -Adrenal Gland Tumors. Most adrenal gland tumors-abnormal growths on the adrenal glands-are not cancerous. Adrenocortical Carcinoma. Cushing Syndrome. Congenital Adrenal Hyperplasia (CAH) Pituitary Tumors. Pheochromocytoma. Adrenal Gland Suppression. Addison’s Disease. More items •31-Jan-2017