GENERAL HISTOLOGY

Detailed explanation-1: -In a negative feedback mechanism, high levels of a hormone turn off further release of that hormone. This usually occurs in a stepwise pattern: the high concentration of the hormone signals back through the system to turn off production of the hormone or hormones that stimulated its release.

Detailed explanation-2: -Negative feedback (or balancing feedback) occurs when some function of the output of a system, process, or mechanism is fed back in a manner that tends to reduce the fluctuations in the output, whether caused by changes in the input or by other disturbances.

Detailed explanation-3: -Positive feedback occurs to increase the change or output: the result of a reaction is amplified to make it occur more quickly. Negative feedback occurs to reduce the change or output: the result of a reaction is reduced to bring the system back to a stable state.