GENERAL HISTOLOGY

Detailed explanation-1: -The inward flow of sodium ions increases the concentration of positively charged cations in the cell and causes depolarization, where the potential of the cell is higher than the cell’s resting potential. The sodium channels close at the peak of the action potential, while potassium continues to leave the cell.

Detailed explanation-2: -During the depolarization phase of the action potential, the charge of the membrane inside the axon changes from positive to negative because of outflow of sodium ions that are having a positive charge.

Detailed explanation-3: -During the depolarization phase, the gated sodium ion channels on the neuron’s membrane suddenly open and allow sodium ions (Na+) present outside the membrane to rush into the cell. As the sodium ions quickly enter the cell, the internal charge of the nerve changes from-70 mV to-55 mV.

Detailed explanation-4: -After a cell has been depolarized, it undergoes one final change in internal charge. Following depolarization, the voltage-gated sodium ion channels that had been open while the cell was undergoing depolarization close again. The increased positive charge within the cell now causes the potassium channels to open.