GENERAL HISTOLOGY

Detailed explanation-1: -Homeostasis is the tendency to resist change in order to maintain a stable, relatively constant internal environment. Homeostasis typically involves negative feedback loops that counteract changes of various properties from their target values, known as set points.

Detailed explanation-2: -What is a negative feedback mechanism? A negative feedback loop is one way that the endocrine system tries to keep homeostasis (stability) in the body. If an endocrine gland senses that there is too much of one hormone in the body, it will initiate changes to decrease production of that hormone.

Detailed explanation-3: -Although negative feedback is more common, some hormone systems are controlled by positive feedback mechanisms, in which a target gland hormone acts back on the hypothalamus and/or pituitary to increase the release of hormones that stimulate the secretion of the target gland hormone.

Detailed explanation-4: -Negative feedback keeps the concentration of a hormone within a relatively narrow range and maintains homeostasis. Very few endocrine hormones are regulated by positive feedback loops. Positive feedback causes the concentration of a hormone to become increasingly higher.

Detailed explanation-5: -The endocrine system is regulated by negative feedback mechanisms that work to maintain homeostasis. The concentration of hormones, and how they effect other body systems, are controlled in this manner. For example, blood glucose regulation is controlled by insulin and glucagon, hormones produced by the pancreas.