GENERAL HISTOLOGY

CONNECTIVE TISSUE GLAND

ENDOCRINE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Hashimoto’s disease is an autoimmune disorder where the body’s own defenses attack the thyroid, causing hypothyroidism. What would be a side effect of Hashimoto’s disease?
A
An increase in the production of thyroid hormones
B
A decrease in the production of thyroid hormones
C
An increase in the production of parathyroid hormones
D
A decrease in the production of parathyroid hormones
Explanation: 

Detailed explanation-1: -Hashimoto’s disease can lead to hypothyroidism, when the thyroid gland is affected and gradually stops producing enough hormones to keep the body working properly. Hashimoto’s is more common in middle-aged women than men and can cause fatigue and weight gain.

Detailed explanation-2: -Hashimoto’s thyroiditis can cause your thyroid to not make enough thyroid hormone. It is an autoimmune disease. It occurs when your body makes antibodies that attack the cells in your thyroid. Symptoms may include an enlarged thyroid gland (goiter), tiredness, weight gain, and muscle weakness.

Detailed explanation-3: -It is caused by a reaction of the immune system against the thyroid gland. The disease begins slowly. It may take months or even years for the condition to be detected and for thyroid hormone levels to become lower than normal. Hashimoto disease is most common in people with a family history of thyroid disease.

Detailed explanation-4: -An autoimmune disorder is an illness caused by the immune system attacking healthy tissues. In Hashimoto’s disease, immune-system cells lead to the death of the thyroid’s hormone-producing cells. The disease usually results in a decline in hormone production (hypothyroidism).

Detailed explanation-5: -Usually if Hashimoto’s disease is suspected due to the signs and/or symptoms a patient develops, a blood test is arranged. This blood test will measure the level of thyroid hormones mainly TSH (thyroid stimulating hormone) and T4 (thyroxine). The level of TSH is the most sensitive indicator of thyroid function.

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