GENERAL HISTOLOGY

Detailed explanation-1: -In primary hyperparathyroidism, one or more of the parathyroid glands is overactive. As a result, the gland makes too much parathyroid hormone (PTH). Too much PTH causes calcium levels in your blood to rise too high, which can lead to health problems such as bone thinning and kidney stones.

Detailed explanation-2: -The parathyroid glands lie behind the thyroid. They produce parathyroid hormone, which plays a role in regulating the body’s blood level of calcium and phosphorus. Hyperparathyroidism is when your parathyroid glands create high amounts of parathyroid hormone in the bloodstream.

Detailed explanation-3: -If calcium blood levels are too low, your parathyroid glands will release PTH into the blood. This causes calcium levels to rise. If calcium blood levels are too high, these glands will stop making PTH. PTH levels that are too high or too low can cause serious health problems.

Detailed explanation-4: -Primary Hyperparathyroidism, which is usually tied to an enlargement (hyperplasia) of a parathyroid gland, a benign (non-cancerous) growth (adenoma) or (in rare cases) a malignant (cancerous) tumor. The reasons for enlargement are usually undetermined but can be hereditary.