GENERAL HISTOLOGY

Detailed explanation-1: -Negative feedback If the blood glucose level is too low, the pancreas releases the hormone glucagon. This travels to the liver in the blood and causes the break-down of glycogen into glucose. The glucose enters the blood stream and glucose levels increase back to normal. This is an example of negative feedback.

Detailed explanation-2: -Negative feedback-example Body temperature is controlled by the hypothalamus in the brain. If the hypothalamus detects that the body is too hot, the response is that the body begins to sweat to try and reduce the temperature back to the correct level.

Detailed explanation-3: -The glucose regulatory system is a classic negative feedback system (Fig. 5–8) maintaining glucose homeostasis. When blood glucose concentration increases after a perturbation, for example, a meal, an oral glucose tolerance test (OGTT) or an intravenous infusion of glucose, the pancreas beta-cells secrete more insulin.

Detailed explanation-4: -Negative Feedback. In a negative feedback loop, feedback serves to reduce an excessive response and keep a variable within the normal range. Examples of processes controlled by negative feedback include body temperature regulation and control of blood glucose.