GENERAL HISTOLOGY

Detailed explanation-1: -The hypothalamus is the master switchboard. It’s the part of the brain that controls the endocrine system. That pea-sized structure hanging below it is the pituitary gland. It’s called the master gland because it regulates the activity of the glands.

Detailed explanation-2: -The pituitary gland is located inferior to the hypothalamus and is connected to the hypothalamus by a stalk. Hormonal secretion by the anterior pituitary is controlled by hypothalamic-releasing hormones that reach their target endocrine tissues in the anterior pituitary via the pituitary stalk.

Detailed explanation-3: -For each system, the hypothalamus secretes releasing hormones (i.e., CRH, GnRH, and TRH) that act on the pituitary gland. In response to those stimuli, the pituitary gland releases ACTH, gonadotropins (i.e., LH and FSH), or TSH. ACTH activates the adrenal glands to release cortisol, which induces metabolic effects.