CONNECTIVE TISSUE GLAND
ENDOCRINE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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the nucleus
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the plasma membrane
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the cytoplasm
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lysosomes
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Detailed explanation-1: -Steroid Hormone Receptors (SHR) act as hormone dependent nuclear transcription factors. Upon entering the cell by passive diffusion, the hormone (H) binds the receptor, which is subsequently released from heat shock proteins, and translocates to the nucleus.
Detailed explanation-2: -Steroid hormone receptors localized in the target cell nucleus have been well documented to play a major role in regulating key genes important for organ development and function.
Detailed explanation-3: -The hormone passes across the target-cell membrane from the circulation and enters the cytoplasm where it binds to a specific protein designated the receptor. A conformational change in the receptor ensues and the receptor-hormone complex is translocated to the chromatin in the cell nucleus.