GENERAL HISTOLOGY

Detailed explanation-1: -The pancreatic islets of Langerhans consist of several hormone-secreting cell types important for blood glucose control. The insulin secreting -cells are the best studied of these cell types, but less is known about the glucagon secreting -cells. The -cells secrete glucagon as a response to low blood glucose.

Detailed explanation-2: -Glucagon is a hormone that works with other hormones and bodily functions to control glucose levels in the blood. It comes from alpha cells found in the pancreas and is closely related to insulin-secreting beta cells, making it a crucial component that keeps the body’s blood glucose levels stable.

Detailed explanation-3: -Alpha cells ( cells) are endocrine cells that are found in the Islets of Langerhans in the pancreas. Alpha cells secrete the peptide hormone glucagon in order to increase glucose levels in the blood stream. Pancreatic islets (islets of Langerhans).

Detailed explanation-4: -The cells make up 25% of the islets of Langerhans and secrete glucagon, a 29-amino-acid peptide, in response to hypoglycemia. The cells synthesize proglucagon which is then cleaved by a proprotein convertase to form glucagon. Glucagon restores blood glucose levels by mobilizing glucose primarily from the liver.

Detailed explanation-5: -Glucagon is a 29-amino acid peptide hormone produced by the alpha () cells of the pancreatic islet. It is known as the primary glucose counter-regulatory hormone, as its main physiological function is to maintain euglycemia by its actions on the liver to promote glycogenolysis and gluconeogenesis.