GENERAL HISTOLOGY

Detailed explanation-1: -Hypothyroidism happens when the thyroid gland doesn’t make enough hormones. Conditions or problems that can lead to hypothyroidism include: Autoimmune disease. The most common cause of hypothyroidism is an autoimmune disease called Hashimoto’s disease.

Detailed explanation-2: -Myxedema coma occurs as a result of long-standing, undiagnosed, or undertreated hypothyroidism and is usually precipitated by a systemic illness. Myxedema coma can result from any of the causes of hypothyroidism, most commonly chronic autoimmune thyroiditis.

Detailed explanation-3: -Myxedema can occur in: Hyperthyroidism, associated with pretibial myxedema and exophthalmos. Pretibial myxedema can occur in 1–4% of patients with Graves’ disease, a cause of hyperthyroidism. Hypothyroidism, including Hashimoto’s thyroiditis.

Detailed explanation-4: -Hashimoto’s disease, an autoimmune disorder, is the most common cause of hypothyroidism. With this disease, your immune system attacks the thyroid. The thyroid becomes inflamed and can’t make enough thyroid hormones.