GENERAL HISTOLOGY

Detailed explanation-1: -Within the hypothalamus are nerve cells that, when activated, produce the sensation of hunger. They do so by producing two proteins that cause hunger: neuropeptide Y (NPY) and agouti-related peptide (AGRP). Quite close to these nerve cells is another set of nerves that powerfully inhibit hunger.

Detailed explanation-2: -Ghrelin is a multifaceted gut hormone which activates its receptor, growth hormone secretagogue receptor (GHS-R). Ghrelin’s hallmark functions are its stimulatory effects on food intake, fat deposition and growth hormone release. Ghrelin is famously known as the “hunger hormone”.

Detailed explanation-3: -Before a meal, the anticipation of eating stimulates the vagus nerve within the brain, which sends a signal to the stomach and stimulate the release of gastrin.

Detailed explanation-4: -This hormone is produced in your stomach and secreted when your stomach is empty. It enters your bloodstream and affects a part of your brain called the hypothalamus, which helps regulate your hormones and appetite ( 4, 7 ). The higher your levels of ghrelin, the hungrier you get.