GENERAL HISTOLOGY

Detailed explanation-1: -Thyroxine (T4) is produced by the thyroid gland under regulation from the hypothalamus and pituitary gland. The feedback loop signals to the hypothalamus in to release thyrotropin-releasing hormone, which then stimulates the pituitary gland to release the thyroid stimulating hormone.

Detailed explanation-2: -The thyroid gland lies in the front of your neck in a position just below your Adam’s apple.

Detailed explanation-3: -Thyrotropin [also known as thyroliberin and thyroid-stimulating hormone (TSH)] is a peptide released by the anterior pituitary gland that stimulates the thyroid gland to release thyroxine (Ladram et al., 1994).

Detailed explanation-4: -Thyroid hormone actually represents the combination of the two main hormones that your thyroid gland releases: thyroxine (T4) and triiodothyronine (T3). They’re often collectively referred to as “thyroid hormone” because T4 is largely inactive, meaning it doesn’t impact your cells, whereas T3 is active.